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Abstract
Systemic lupus erythematosus is a chronic (SLE), multisystemic autoimmune disease of unknown etiology that mainly affects women of reproductive age. The prevalence of the disease varies according to the region, oscillating in a range of 20 to 150 cases per 100,000 inhabitants, during pregnancy the activity of lupus is variable, improving in 33%, remaining unchanged in 33% and worsening in other 33%. The preconception evaluation constitutes a fundamental component of the initial management with the purpose of determining the appropriate time to conceive a pregnancy where this does not imply an unacceptably high maternal or fetal risk; as well as adjust compatible treatment for disease control during pregnancy. The following article focuses on providing updated information on the general management of SLE during the preconception period, treatment measures during pregnancy and the main maternal-fetal complications associated with pregnancy in patients with SLE.
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References
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